Robert J. Mentz, MD is an Associate Professor of Medicine with Tenure and Chief of the Heart Failure Section at Duke University. He is the Editor-in-Chief of the Journal of Cardiac Failure – the official journal of the Heart Failure Society of America.

Robert spends his clinical time at Duke University Hospital assisting with the care of patients with heart failure, cardiac transplants and ventricular assist devices.

He is a leading clinical trialist in both traditional and pragmatic studies. He was the clinical lead for the HEART-FID trial of IV iron in 3065 participants. He served as Co-PI for the NIH-funded TRANSFORM-HF pragmatic trial of loop diuretics in 2,859 patients with heart failure and PI of the PARAGLIDE-HF trial of sacubitril/valsartan in acute HFpEF. He has published >500 manuscripts—many with current or former trainees as the first author.

He has expertise in trial design and execution that supports the inclusion of diverse participants. He is a leader in site engagement with efficient recruitment that streamlines clinical studies while optimizing data quality.

He is a Co-PI for the FDA’s Research Triangle CERSI (Center of Excellence in Regulatory Science and Innovation).

He is an established mentor for medical students, residents and fellows and was the recipient of the 2021 Clinical Research Mentoring Award from the Duke School of Medicine and the W. Proctor Harvey Award from the American College of Cardiology.