Stephanie Wethignton, MD. MSc

Professional Experience
Associate Director (Acting) | Oncology Center of Excellence (OCE), U.S. Food & Drug Administration
- Associate Director (Acting) of Education & Gynecologic Oncology, Oncology Center of Excellence, July 2025 to present
- Lead strategy for internal and external partnerships (ex. across FDA Centers and with professional organizations and patient advocacy groups) that facilitate the mission of the OCE
- Support the professional development of the OCE/OND physician staff
- Provide expert guidance on clinical development of gynecologic oncology drugs, from phase 1 through review of marketing applications & post-marketing pharmacovigilance, ensuring alignment with evidence-based & regulatory standards
- Cross-Center Team Lead, Oncology Review, September 2024 to present
- Physician, November 2023 to July 2025
Assistant Professor, Gynecologic Oncology | Johns Hopkins Medicine | 2017 to present
- Authored or co-authored more than 60 peer-reviewed manuscripts on improving health care outcomes, use of digital applications to facilitate screening for social determinants of health, and the management of gynecologic cancers https://www.ncbi.nlm.nih.gov/myncbi/1BAqVjCCEkEkf/bibliography/public/
- Principal or co-investigator on more than $3 million in grant funding, including NIH ovarian & cervical cancer P50 SPORE grants
- Contributed to the Society of Gynecologic Oncology Clinical Care Guidelines and served on the National Comprehensive Cancer Network® (NCCN) Committee for Uterine, Cervical, Vulvar/Vaginal and Gestational Trophoblastic Neoplasia
- Delivered, chaired or moderated 200+ lectures, conferences, & workshops nationally/internationally
- Board certified in Gynecologic Oncology and Obstetrics & Gynecology, Active DC & Maryland Medical Licenses
Physician Advisor and Vice Chair of Quality, Safety & Service | Department of Gynecology and Obstetrics,
The Johns Hopkins Hospital | 2022 to 2023
- Implemented department level quality improvement, patient safety & high value care initiatives as the leader of a multidisciplinary team & while engaging a diverse group of stakeholders
- Served as department liaison to hospital leadership & to clinical and administrative departments across the institution
- Managed medical staff affairs including credentialing & peer review
- Directed utilization & risk management, billing, coding, & regulatory functions
Director, Clinical Operations | The Kelly Gynecologic Oncology Service, Johns Hopkins Medicine | 2020 to 2023
- Led multidisciplinary teams to
- operationalize gynecologic cancer care during the COVID-19 pandemic - maintained clinical capacity, launched telemedicine & work from home programs, developed perioperative protocols, established remote rounding, conducted outreach to patients & providers
- instituted universal social resource needs screening & resource referral to improve health equity
- implement clinical care pathways to address opioid prescribing, venous thromboembolism prophylaxis, & integration of palliative care into standard oncology care
- Designed gynecologic oncology resident education program
- Represented the Division, including to the Cancer Center, Operating Room Executive, & Compensation Committees
- Medical Director of the Gynecologic Oncology inpatient unit & ambulatory clinics
Director | Susan L Burgert Gynecologic Oncology Survivorship Program, Johns Hopkins Medicine | 2017 to 2022
- Provided support services for gynecologic cancer patients & caregivers to improve patient outcomes through peer-mentorship, patient and caregiver retreats & counseling services. Raised over $1 million to support the programming.
Gynecologic Oncologist | MidAtlantic Gynecologic Oncology and Pelvic Surgery Associates | 2013 to 2016
Representative Activities
Member | 2023 to present | Board of Directors, Hopewell Cancer Support
Core Member | 2022 to 2023 NRG Oncology Ovarian Cancer Core Committee (NCI cooperative research group)
Member | 2017 to 2023 | High Value Practice Alliance | Conference Committee 2018 to 2022
Member | 2009 to present | The Society of Gynecologic Oncology
- Legislative and Regulatory Affairs Committee | 2017 to 2023 | Chair 2021 to 2023
- Policy, Quality & Outcomes Taskforce | 2017 to 2021
Education and Training
Fellowship | 2009 to 2013 | Memorial Sloan Kettering Cancer Center | Administrative Chief 2012 to 2013
Residency | 2006 to 2009 | Sloane Hospital for Women, Columbia University | Chief Resident 2008 to 2009
Internship | 2005 to 2006 | Magee-Womens Hospital, University of Pittsburgh, Pittsburgh, PA
Doctor of Medicine | 2005 | College of Physicians & Surgeons, Columbia University, New York, NY
Master of Science, Economic & Social History | 2000 | University of Oxford, Oxford, United Kingdom
Bachelor of Arts, English and American Literature | 1999 | Brandeis University, Waltham, MA

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