1. Personal Statement:

I am an Assistant Professor of Pediatrics and have a focused interest in pediatric hematology especially in sickle cell disease, hemoglobinopathies and bleeding and thrombosis. I have worked on clinical research to reduce the burden of thrombosis in high-risk populations, including evaluating the role of prophylactic anticoagulation in patients with malignant mediastinal masses and presently working on studying risk factors of developing thrombosis in the small bowel, liver transplant cohort. I am the clinical director of the pediatric sickle cell program at Medstar Georgetown University Hospital and have established a strong comprehensive pediatric and young adult sickle cell comprehensive clinic. I also have a strong interest in medical education and am the course director of the Pediatric Hematology Oncology elective at Georgetown University Medical Center.

Positions and Honors:

Positions and Employment:

2009-2011       Clinical Instructor in Pediatrics, SUNY, Stony Brook, NY

2011-2014       Clinical Instructor in Pediatrics, Hofstra School of Medicine, NSLIJ,

2015-2018       Pediatrician, Olde Towne Pediatrics, Manassas, VA

2019-               Assistant Professor, Pediatric Adolescent and Young Adult Hematology and Oncology, Medstar Georgetown University Hospital

Honors and Awards

03/2020           Faculty Development Travel Award

08/2019           American Society of Hematology Medical Educator’s Institute Award Recipient

2013                Sponsored to Attend HTRS Coagulation Disorders Workshop

2012                Sponsored to Attend Center for advanced training in inhibitor management

08/2007           National winner (India) of the Indian Academy of Pediatrics                                                             Postgraduate Quiz in Neonatology.

05/2002           Stem Cells. Runner up at the Bombay Medical Congress Symposium.

05/1999           Gold Medal and Biology Scholarship by Department of Biotechnology,

Ministry of Science and Technology, Govt. of India for outstanding performance in Biology.

06/1999           Certificate of Merit by the Central Board of Secondary Education,                                                             India for outstanding performance in Chemistry and Biology at the      

                        All India Senior School Certificate Examination.

2. Contributions to Science:

1. Use of a Bleeding Questionnaire to Predict Risk of Intra-operative Bleeding in Children. Yes/No Questionnaire devised to be filled by parents preoperatively and correlated with bleeding symptoms and preoperative coagulation tests. 07/2012-10/2019
2. Prophylactic anticoagulation to prevent thromboembolic events  in pediatric oncology patients with a mediastinal mass.Retrospective chart review evaluating the potential of prophylactic anticoagulation. 02/2013-10/2019 
3. Cholinergic regulation of Hemostasis. Elucidating the mechanism by which vagal nerve stimulation controls bleeding in a Hemophilia A mouse model. 04/2013-06/2014
4. Evaluation of different stem cell populations as candidate leukemic stem cells via surface CD markers, novel nanoparticle ligands and Raman spectroscopy. 08/2008-06/2009

3. Scholastic Performance/Publications:

1. Martin SD, Davis ES, Dai C, et al. Clinical Features and Risk Factors Associated With Multisystem Inflammatory Syndrome in Children With Cancer and COVID-19. JAMA Oncol. (Member of POCC Consortium)Published online May 11, 2023. doi:10.1001/jamaoncol.2023.0525
2. Huston J, Bravo-Iniguez C, Fritz J, Shukla S, Sarangi S, Thompson D, Amin S, Tsaava T, Chaudhry S, Valentino S,  Hoffman H, Imossi C, Addorisio M, Valdés-Ferrer S,  Chavan S, Blanc L, Czura C, Tracey K. Vagus nerve stimulation primes platelets and reduces bleeding in hemophilia A male mice. Nat Commun 14, 3122 (2023). https://doi.org/10.1038/s41467-023-38505-6
3. Cumming D, Schreiber J, Magaziner S, Sarangi S. Revisiting cycloid psychosis: An unexpected approach to a diagnostic challenge, Psychiatry Research Case Reports, Volume 1, Issue 1, 2022. https://doi.org/10.1016/j.psycr.2022.100008.

4. Rabinovich E, Johnson-Arbor K, Serrano M, Chao C, Eblan M, Rao A, Terao M, Toretsky J, Sarangi, S, Varela C, Hong D. The use of hyperbaric oxygen therapy in the management of severe radiation-induced hemorrhagic gastritis in a pediatric patient. JPGN reports (Accepted Oct 2021)
5. Sarangi SN, Gaballah M, Nolfi-Donegan D, et al. Primary thromboprophylaxis to prevent thrombotic events in pediatric oncology patients with a malignant mediastinal mass. Pediatr Blood Cancer. 2021;e29360. https://doi.org/10.1002/pbc.29360.
6. Singh JK, Terao M, Sarangi S, Toth J, Toretsky J. Afebrile S. aureus bacteremia in two patients with hemophagocytic lymphohistiocytosis receiving emapalumab/dexamethasone/etoposide. Pediatric Blood and Cancer 2021; e29001. https://doi.org/10.1002/pbc.29001
7. Sarangi S, Acharya S. Bleeding Risk in Renal Disease. In: Shaz B, Hillyer C, Gil MR eds. Transfusion Medicine and Hemostasis, Clinical and Laboratory Aspects. 3^rd ed.  Elseiver 2019. P 739-742
8. Singh S, Sarangi S, Appiah-Kubi A, Hsu P, Smith B, Gallagher P, Glader B, Chui D. Hb Adana (HBA2 or HBA1: c.179G>A) and alpha thalassemia: genotype-phenotype correlation. Pediatric Blood and Cancer 2018; e27220. https://doi.org/10.1002/pbc.27220
9. Sarangi S, Acharya S. 2016. Bleeding Disorders in Congenital syndromes. Pediatrics; Jan 2017, e20154360; DOI: 10.1542/peds.2015-4360
10. Sarangi S, Acharya S. 2016.  Disorders of Coagulation.  In: Lanzkowsky P. 6^th ed.  Manual of Pediatric Hematology and Oncology. Elseiver 2016. 279-332.
11. Sarangi S, Wolfe L. VHL Homozygous VHL D126N. Congenital Erythrocytosis and Hereditary Thrombocytosis. European Cooperation in Science and Technology (COST). 2015
12. Sarangi S, Lanikova L, Kapralova K, Acharya S, Lipton JM, Wolfe L Prchal J. The homozygous VHL ^D126N missense mutation is associated with dramatically elevated erythropoietin levels, consequent polycythemia and early onset severe pulmonary hypertension. Pediatr Blood Cancer, 61: 2104-2106. doi:10.1002/pbc.25056
13. Sarangi S, Golightly M, Weber J, Chan J. A family with Bolzano-type Bernard-Soulier syndrome carries a benign A1939T MYH9 mutation. Platelet 2013; 24 (1): 81-84
14. Satake N, Lee J, Xiao K, Luo J, Sarangi S, Chang A, Nolta J, Lam K; Nanoparticle targeted therapy against childhood acute lymphoblastic leukemia. Proc. SPIE 8031, Micro- and Nanotechnology Sensors, Systems, and Applications III, 80311U (May 13, 2011); doi:10.1117/12.885550